Emory University;Hauptman-Woodward Medical Research Institute;The Research Foundation of State of New York
发明人:
Davies, Huw,Ghosh, Debashis,Morton, Daniel
申请号：
AU2011237592
公开号：
AU2011237592A1
申请日:
2011.04.07
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The disclosure relates to novel C4 and C6 substituted androst-4-ene diones as well as andros-1,4-diene diones and derivatives thereof, their process of preparation, pharmaceutical compounds containing them, and the use of said compounds for the treatment of hormone-related disorders in mammals. This includes hormone-dependent cancers, particularly those caused by elevated levels of estrogen and its intermediates. These compounds can also be used in the treatment of other hormone-related disorders, inluding benign prostatic hyperplasia, cardiovascular disease, and neurodegenerative disorders.
