A heparanase activity inhibitor comprising, as an active ingredient, a cyclic carboxamide derivative represented by formula (I): wherein n is an integer of 1 to 3, R 1 is hydrogen or a C1-6 hydrocarbon group optionally substituted with hydroxyl, X is -CH 2 - or a group represented by -N(R 2 )-, and R 2 is hydrogen or a C1-6 hydrocarbon group optionally substituted with hydroxyl, or a salt thereof.
