PROBLEM TO BE SOLVED: To provide a method of producing an indole compound useful for a therapeutic or prophylactic agent for inflammatory diseases, allergic diseases and autoimmune diseases and an agent for suppressing rejection in organ transplantation.SOLUTION: This invention provides a method of producing an indole compound such as N-[2-(6,6-dimethyl-4,5,6,7-tetrahydro-1H-indazol-3-yl)-1H-indol-6-yl]-N-methylacetamide through a reaction represented by, for example, the following formula.【課題】炎症性疾患、アレルギー性疾患、自己免疫疾患の治療または予防剤、及び移植における拒絶反応の抑制剤等に有用な化合物の製造方法の提供。【解決手段】下記式のような反応を経る、N-[2-(6,6-ジメチル-4,5,6,7-テトラヒドロ-1H-インダゾール-3-イル)-1H-インドール-6-イル]-N-メチルアセトアミド等のインドール化合物の製造方法。【選択図】なし