AGENT MÉDICINAL POUR LE TRAITEMENT DE LA SCLÉROSE LATÉRALE AMYOTROPHIQUE OU LA PRÉVENTION DE L'ÉVOLUTION D'UNE PHASE DE LA SCLÉROSE LATÉRALE AMYOTROPHIQUE
The purpose of the present invention is to provide a novel medicinal agent and a novel method both of which can be used for treating ALS (amyotrophic lateral sclerosis), preventing the progression of the phase of ALS, treating a symptom associated with ALS, or preventing the progression of the phase of the symptom, and both of which can be particularly applied to patients who can be treated by the medicinal agent or the method highly effectively among ALS patients who are needed to be treated. According to the present invention, a medicinal agent which can be used for treating amyotrophic lateral sclerosis, preventing the progression of the phase of amyotrophic lateral sclerosis, treating a symptom associated with amyotrophic lateral sclerosis, or preventing the progression of the phase of the symptom is provided. The medicinal agent comprises 3-methyl-1-phenyl-2-pyrazolin-5-one or a physiologically acceptable salt thereof as an active ingredient, is administered in such a manner that a 14-day dosing period and a 14-day washout period are repeated alternately or in such a manner that a 14-days initial dosing period and a subsequent 14-day initial washout period are set and subsequently a dosing period in which the dosing is carried out for any 10 days of 14 days and a 14-day washout period are repeated alternately, and is administered to a patient who meets specific criteria.La présente invention concerne un nouvel agent médicinal et un nouveau procédé qui peuvent tous deux être utilisés pour traiter la SLA (sclérose latérale amyotrophique), prévenir l'évolution de la phase de SLA, traiter un symptôme associé à la SLA, ou prévenir l'évolution de la phase du symptôme, et tous deux pouvant être en particulier appliqués à des patients qui peuvent être traités très efficacement par l'agent médicinal ou le procédé parmi l'ensemble des patients atteints de SLA qui nécessitent un traitement. La présente invention concerne un agent médicinal qui peut être utilisé pour trait
