inactivated split influenza virus of strain a \/ indonesia \/ 05 \/ 2005 (h5n1) (pr8 - ibcdc - rg2), if a pandemic strain in an officially declared pandemic situation
There is disclosed a method for generating in cultured cells infectious viral particles of a segmented negative-strand virus by an entirely vector-based system without the aid of a helper virus. The method may, for example, be particularly useful for producing modified influenza viruses.