The Trustees of Columbia University in the City of New York
发明人:
Stephen H. TSANG,Xuan CUI,Pei-Yin SU,Sally JUSTUS
申请号:
US16613616
公开号:
US20200172927A1
申请日:
2018.05.15
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure relates to methods and compounds for promoting anabolic pathways in neuronal cells leading to improved neuronal survival. In particular, the present disclosure relates to inhibiting YHL/Vhl to promote glycolysis and neuronal survival in a variety of neurodegenerative conditions, and specifically in retinitis pigmentosa.