Ezio Bonvini,Leslie S. Johnson,Ling Huang,Paul A. Moore,Gurunadh Reddy Chichili,Ralph Froman Alderson
申请号：
US14913632
公开号：
US09822181B2
申请日:
2014.08.20
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention is directed to sequence-optimized CD 123×CD3 bi-specific monovalent diabodies that are capable of simultaneous binding to CD 123 and CD3, and to the uses of such diabodies in the treatment of hematologic malignancies.
