BOYCE, RUSTUM,MARTIN, ERIC,WANG, WEIBO,YANG, HONG,BARSANTI, PAUL A
申请号:
NZ57772708
公开号:
NZ577727A
申请日:
2008.01.03
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a compound or a pharmaceutically acceptable salt or ester thereof having the Formula (I), wherein the substituents are disclosed in the specification. Also disclosed is the use of the compound for the manufacture of a medicament for treating a cellular proliferative disease. Also disclosed is a method for inhibiting the activity of KSP kinesin which method comprises contacting said kinesin with an effective inhibitory amount of the said compound, wherein, for any human subject, the method is performed ex vivo.