This invention relates to a hyaluronic acid enzyme inhibitor having excellent hyaluronic acid enzyme inhibition function more specifically, it is to provide a hyaluronic acid enzyme inhibitor that contains rosemary extracts having hyaluronic acid enzyme inhibition function and retinyl acetate that is capable of enhancing hyaluronic acid enzyme inhibition function of the rosemary extracts.本發明係關於提供一種具有優異之玻尿酸酶抑制作用之玻尿酸酶抑制劑。更具體而言,提供一種包含具有玻尿酸酶抑制作用之迷迭香萃取物、及增強迷迭香萃取物之玻尿酸酶抑制作用之乙酸視黃酯的玻尿酸酶抑制劑。