GALOPIN CHRISTOPHE,KRAWEC PABLO VICTOR,SLACK JAY PATRICK,TIGANI LORI
申请号：
IN1756/CHENP/2006
公开号：
IN250921B
申请日:
2006.05.19
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
Compounds of the formula (I) give a cooling sensation to the mouth and skin. In Formula I, m is 0 or 1, Y and Z are selected independently from the group consisting of H, OH, C1-C4 straight or branched alkyl, or, a C1-C4 straight or branched alkoxy, X is (CH2)n-R, where n is 0 or 1 and R is a group with non-bonding electrons, with the provisos that: (a) when Y and Z are H, X is not F, OH, MeO or NO2 in the 4-position and is not OH in the 2 or 6-position (b) when Y or Z is H then X, Y and Z are such that (i) the groups in the 3- and 4-positions are not both OMe, (ii) the groups in the 4- and 5-positions are not both OMe, (iii) the groups in 3- and 5-positions are not OMe if the group in the 4-position is OH, and (iv) the groups in the 3- and 5-positions are not OH if the group in the 4-position is methyl. The compounds give a cooling sensation up to ten times more powerful than the best current commercial materials.
