COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER

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专利权人:

The Regents of the University of California

发明人:

Allen C. Gao,Yezi Zhu

申请号：

US15796211

公开号：

US20180153850A1

申请日:

2017.10.27

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Methods and compositions are provided for treatment of cancer, including prostate cancer. In one aspect, the present invention provides a composition comprising a taxane and a drug that reduces efflux of the taxane from a cell. The drug that reduces efflux of the taxane can be an inhibitor of ABCB1 efflux activity. In some cases, the inhibitor of ABCB1 efflux activity is an inhibitor of ABCB1 ATPase activity selected from the group consisting of enzalutamide and bicalutamide.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/