DR. REDDY&rsquo；S LABORATORIES LTD.;DR. REDDY&rsquoS LABORATORIES LTD.
发明人:
BORUAH ANIMA,ALIKUNJU SHANAVAS
申请号：
NZ62091412
公开号：
NZ620914A
申请日:
2012.08.17
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed herein are cycloalkylpyridin-2-amines of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof. The present application also relates to the process for the preparation of compounds of formula (I). The present application further describes the compounds of formula (I) as cholesteryl ester-transfer protein (CETP) inhibitors. The present application further relates to pharmaceutical compositions comprising compounds of formula (I) or stereoisomers thereof or pharmaceutically acceptable salts thereof. Particular examples of the compounds of formula I include 3-(((3,5-bis(trifluoromethyl)benzyl)(5-bromopyrimidin-2-yl)amino)methyl)-N,N-bis(cyclopropylmethyl)-7,7-dimethyl-6,7-dihydro-5H-cyclopenta[b]pyridin-2-amine and 3-(((3,5-bis(trifluoromethyl)benzyl)(2-methyl-2H-tetrazol-5-yl)amino)methyl)-N,N-bis(cyclopropylmethyl)-8,8-dimethyl-5,6,7,8-tetrahydroquinolin-2-amine.
