There is provided processes and uses of an inline saturator for maintaining fish in a cage in an open body of water, the process comprising: restricting movement of water into and out of a part of the cage and forming a portion of water within the part of the cage. The process also includes injecting oxygenated water produced by an inline saturator into the portion of water to raise a dissolved oxygen level and to lower a dissolved nitrogen gas level therein. A treatment process is also provided that includes the steps noted above and further including introducing a medicinal substance into the oxygenated water or the portion of the body of water.