Maria Graca N.D. Almeida-Porada,Christopher D. Porada,Colin E. Bishop
申请号：
US14931899
公开号：
US20160130554A1
申请日:
2015.11.04
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Method for reprogramming of stromal cells into hematopoietic cells are provided. Also provided are mesenchymal stromal cells that can be reprogrammed into hematopoietic cells. In addition, hematopoietic cells reprogrammed from mesenchymal stromal cells are provided. Reprogramming stromal cells into hematopoietic cells is effected through a vector encoding a transcription factor that controls hematopoietic cell differentiation. Methods of treating subjects having diminished hematopoietic cell populations are provided as well.
