Chih-Cheng Chen,Yun-Lian Lin,Jim-Min Fang,Yijuang Chern,Chia-Ching John Lin,Wei-Nan Chen,Chun-Jung Lin
申请号:
US15376281
公开号:
US20170224716A1
申请日:
2016.12.12
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides a new use of adenosine analogs for the treatment of pain through activation of neurokinin 1 (NK1) receptor signaling pathway, thereby inducing the activation of activation of M-type potassium channel to induce outward currents. A method and pharmaceutical composition for treating pain comprising an adenonsine analog that activates NK1 receptor signaling, thereby inducing outward current are also provided.