JACKSON, SIMON MARK,WALKER, NIGEL PELHAM CLINTON,PIPER, DEREK EVAN,SHAN, BEI,SHEN, WENYAN,CHAN, JOYCE CHI YEE,KING, CHADWICK TERENCE,KETCHEM, RANDAL ROBERT,MEHLIN, CHRISTOPHER,CARABEO, TERESA ARAZAS,Q
申请号：
PE2013000883
公开号：
PE20140220A1
申请日:
2008.08.22
申请国别(地区):
PE
年份:
2014
代理人:
摘要：
This refers to an uncompetitive Neutralizing Antigen from a polymerized protein to LDLR, including a series of amino acids of SEQ ID 1, selectively binding the polymerized protein to acrylonitrile / kexina class 9 (PCSK9). An antibody and a preparation method are also mentioned This combined protein is useful in the treatment of high cholesterol, etcREFERIDA A UNA PROTEINA DE UNION A ANTIGENO NEUTRALIZADORA NO COMPETITIVA DE LDLR QUE COMPRENDE UNA SECUENCIA DE AMINOACIDOS DE SEQ ID N�1, DONDE DICHA PROTEINA DE UNION SE UNE SELECTIVAMENTE A PROPROTEINA CONVERTASA SUBTILISINA/KEXINA TIPO 9 (PCSK9). TAMBIEN ESTA REFERIDA A UN ANTICUERPO Y A UN METODO DE PREPARACION. DICHA PROTEINA DE UNION ES UTIL EN EL TRATAMIENTO DE LA HIPERCOLESTEROLEMIA, ENTRE OTROS
