Processes and apparatuses for the production of crystalline organic microparticle compositions by micro-milling and crystallization on micro-seed and their use
Lee, Ivan,Cote, Aaron,Johnson, Brian K.,Starbuck, Cindy,Tung, Hsien Hsin,Midler, Michael
申请号：
AU2007226626
公开号：
AU2007226626B8
申请日:
2007.03.12
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to a process, for the production of crystalline particles of an active organic compound The process includes the steps of generating a micro-seed by a wet-milling process and subjecting the micro-seed to a crystallization process. The resulting crxystalline particles have a mean particle size of less than about 100 μm. The present invention also provides for a pharmaceutical composition which includes the crystalline particles produced by the method described herein and a pharmaceutically acceptable carrier.
