1,2,4-OXADIAZOLD DERIVATIVES AS IMMUNE MODULATORS

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专利权人:

Aurigene Discovery Technologies Limited

发明人:

SASIKUMAR, Pottayil Govindan Nair,RAMACHANDRA, Muralidhara,NAREMADDEPALLI, Seetharamaiah Setty Sudarshan

申请号：

DK14790320

公开号：

DK3041827T3

申请日:

2014.09.05

申请国别(地区):

DK

年份:

2018

代理人:

摘要：

The present invention relates to 1,2,4-oxadiazole and 1,2,4-thiadiazole compounds as therapeutic agents capable of inhibiting the programmed cell death 1 (PD1) signaling pathway. The invention also refers to derivatives of the therapeutic agents. The invention also encompasses the use of the said therapeutic agents and derivatives for treatment of disorders via immunopotentiation comprising inhibition of immunosuppressive signal induced due to PD-1, PD-L1, or PD-L2 and therapies using them.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/