Compounds and compositions are disclosed in which a Drug Unit is linked to a targeting Ligand Unit through a self-stabilizing Linker Unit from which a drug compound or active drug moiety is released at the targeted site of action. Methods for treating diseases characterized by the targeted abnormal cells, such as cancer or an autoimmune disease using the compounds and compositions of the invention are also disclosed.本發明揭示藥物單元經由自我穩定連接子單元連接至靶向配體單元之化合物及組合物，藥物化合物或活性藥物部分在靶向作用位點處自該化合物及組合物釋放。 亦揭示使用本發明之該等化合物及組合物來治療特徵在於靶向異常細胞之疾病(例如癌症或自體免疫疾病)之方法。
