BANDARU RAJ,HAIDER ASIFA,ROBINSON DOUGLAS MICHAEL,ROSE KRISTINE LYNN,SHARP THAD TYSON,SHOU YAPING
申请号：
NZ61742112
公开号：
NZ617421A
申请日:
2012.04.03
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Discloses a method of predicting response to treatment with a Hedgehog signalling inhibitor, the method comprising determining the level of expression of at least two biomarkers selected from the group consisting ofGLI-1, OTX-2, SHROOM2, PDLIM3, SPHK1, SFRP1, APBA2 and SP ATA20, in a biological sample derived from a subject having cancer, thereby to predict an increased likelihood of response to a Hedgehog signalling inhibitor.
