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Self-assembly of therapeutic agent-peptide nanostructures
专利权人:
发明人:
Jonathan R. Parquette,Se Hye Kim,Mark W. Grinstaff,Jonah A. Kaplan
申请号:
US14095816
公开号:
US10098967B2
申请日:
2013.12.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed are conjugates of hydrophobic drugs linked to protected or unprotected amino acids or peptides. The disclosed conjugates are amphiphilic and can self assemble into nantubes. Nanotubes comprising the conjugates are also described and can have high loading of the drug and protect it from degradation or elimination. The nanotubes are well suited to deliver hydrophobic and unstable drugs to individuals.
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