PROBLEM TO BE SOLVED: To provide a composition containing a compound having strong astrocyte differentiation promoting action.SOLUTION: The present invention provides a pharmaceutical composition or food composition containing a coronarin derivative represented by formula (I), or a solvate thereof (R1 is H or OH X-Y is CH2-CH2, CH=CH or CH2-CH=, or X-Y is not included and R2 and decahydronaphthalene ring directly bond to each other R2 is a furan ring, a dihydrofuran ring or the like).SELECTED DRAWING: Figure 5COPYRIGHT: (C)2019,JPO&INPIT【課題】強いアストロサイト分化促進作用を有する化合物を含有する組成物の提供。【解決手段】式(I)で表されるコロナリン誘導体、又はその溶媒和物を含有する医薬組成物又は食品組成物。(R1はH又OH;X-YはCH2-CH2、CH=CH或いはCH2-CH=又はX-Yは含まれずR2とデカヒドロナフタレン環が直接結合;R2はフラン環、ジヒドロフラン環等)【選択図】図5
