Embodiments of the present invention provide processes for preparing thymus extracts and plant or fungal extracts, and more particularly provide compositions (Thyex-1-6A and -6B) produced in accordance with said processes, and methods for treatment of various conditions comprising administration of said compositions including but not limited to arthritis and/or arthritis-related conditions, including: gout, rheumatoid arthritis (RA), osteoarthritis (OA), and pseudogout, and/or inflammation resulting from any of the conditions Additional aspects provide methods for combination or adjunctive therapies (with anti-inflammatories, etc.). Methods to modulate immune response are also encompassed.
