The invention relates to compounds of structural formula (I):or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein R1, X1, X2, Y, Z, L, and n are defined herein. The compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.本發明關於具結構式(I)之化合物或其醫藥上可接受之鹽、溶劑合物、晶籠化合物、或前藥：式中：R1、X1、X2、Y、Z、L及n皆如本文中所定義者。該等化合物可用於作為免疫抑制且用於治療或預防炎性狀況、過敏性失調及免疫失調。
