Novel compounds having structure (1)wherein Z, Y, R1, R2and R2are defined in the specification, are provided for use in the treatment of tumors and the prophylaxis or treatment of viral infections.本發明提供了用於治療腫瘤並預防或者治療病毒感染的具有結構(1)的新的化合物,其中Z、Y、R1、R2′和R2在說明書中定義。