WELS, WINFRIED,WALDMANN, ANJA,ZHANG, CONGCONG,KAULICH, MANUEL
申请号:
CA3079076
公开号:
CA3079076A1
申请日:
2018.10.18
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention pertains to methods and compounds useful in a therapy involving the administration of immune cells to a patient. The method of the invention involves the modification of cells of the immune system with agonists or antagonists of immune regulators such as Interleukin-10 (IL-10) or IL-6, in order to enhance and improve the immunological potential of the immune cells for therapy. Cells modified according to the method of the invention can be administered to a patient to support a treatment of proliferative diseases such as cancer or autoimmune disorders.