Benzodiazepinska spojina in farmacevtski sestavek

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专利权人:

LTD.;OTSUKA PHARMACEUTICAL CO.

发明人:

OSHIMA KUNIO,OSHIYAMA TAKASHI,TAIRA SHINICHI,MENJO YASUHIRO,YAMABE HOKUTO,MATSUMURA SHUUJI,UEDA MASATAKA,KOGA YASUO,TAI KUNINORI,NAKAYAMA SUNAO,ONOGAWA TOSHIYUKI,TSUJIMAE KENJI,OSHIMA Kunio,OSHIYAMA Takashi,TAIRA Shinichi,MENJO Yasuhiro,YAMABE Hokuto,MATSUMURA Shuuji,UEDA

申请号：

SI200930958

公开号：

SI2254873T1

申请日:

2009.02.20

申请国别(地区):

SI

年份:

2014

代理人:

摘要：

The present invention provides a novel benzodiazepine compound that blocks the IKur current or the Kv1.5 channel potently and more selectively than other K+ channels. The benzodiazepine compound of the invention is represented by General Formula (1) wherein R1, R2, R3, and R4 are each independently hydrogen or lower alkyl； R2 and R3 may be linked to form lower alkylene； A1 is lower alkylene optionally substituted with one or more hydroxy； and R5 is group represented by wherein R6 and R7 are each independently hydrogen or organic group； XA and XB are each independently bond, lower alkylene, etc.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/