Provided are pyrrolyl substituted dihydroindol-2-one derivatives represented by formula (I), pharmaceutically acceptable salts or solvates thereof, or solvates of said salts, which are effective tyrosine kinase inhibitors. Also provided are the preparation methods of the above compounds, pharmaceutical compositions containing these compounds, and the uses of these compounds in manufacturing drugs useful for the treatment or adjunctive treatment of tumors mediated by tyrosine kinases or proliferation or migration of tumor cells driven by tyrosine kinases in mammals (including human).
