The present invention relates to the compound of formula which is 4-hydroxy-4-methyl-piperidine-1-carboxylic acid(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide, and to pharmaceutically acceptable acid addition salts thereof. It has been found that the compound is useful for the treatment or prevention of Alzheimer's disease, Parkinson's disease, Huntington's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, ADHD (attention deficit hyper-activity disorder), drug addiction to amphetamines, cocaine, opioids, ethanol, nicotine, or cannabinoids, or for the treatment of asthma, allergic responses, hypoxia, ischemia, seizure, substance abuse, or for use as muscle relaxants, antipsychotics, antiepileptics, anticonvulsants and cardioprotective agents.本發明係關於一種式I化合物，即4－羥基－4－甲基－六氫吡啶－1－羧酸(4－甲氧基－7－嗎福林－4－基－苯并噻唑－2－基)－醯胺及其醫藥上可接受的酸加成鹽。已經發現該化合物可用於治療或預防阿爾茨海默氏病(Alzheimer's disease)、帕金森氏病(Parkinson's disease)、亨廷頓氏病(Huntington's disease)、神經保護、精神分裂症、焦慮症、疼痛、呼吸不足症、抑鬱症、ADHD(注意力缺陷性多動症)、對安非他命(amphetamine)、可卡因、類罌粟鹼、酒精、尼古丁、大麻素類物質等藥物成癮，或者用於治療哮喘、過敏性反應、缺氧、缺血、癲癇發作、物質濫用，或用作肌肉鬆弛劑、抗精神病藥、抗癲癇藥、抗驚厥藥及心血管保護劑。
