SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1 -[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYTALLINE FORMS THEREOF

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

ROTHENHAEUSLER, BENNO,TRUSSARDI, RENÉ,HOFFMANN-EMERY, FABIENNE,SCHWITTER, URS,ADAM, JEAN-MICHEL,GRASSMANN, OLAF,HARTUNG, THOMAS,RAN, FREDERIC,DIODONE, RALPH,PFLEGER, CHRISTOPHE,BARTELS, BJOERN

申请号：

SG11201604502S

公开号：

SG11201604502SA

申请日:

2014.12.01

申请国别(地区):

SG

年份:

2016

代理人:

摘要：

The present invention provides processes to manufacture substituted 1-[4-(Pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulenes. Also disclosed are compounds useful as intermediates in the methods of the invention.

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