Scott Malcolm,Carrie Bowen,Laurence Melnick,Linghong Xie
申请号:
US14352294
公开号:
US09580409B2
申请日:
2012.11.07
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided herein are compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as pain, neurological disorders, psychiatric disorders, and neuromuscular disorders. Compounds provided herein modulate the activity of opioid receptor (e.g., μ-opioid receptor) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.