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COMPOSITIONS ET METHODES DE VACCINATION ANTI-TUMORALE UTILISANT DES ANTIGENES ASSOCIES AU CANCER DE LA PROSTATE
专利权人:
ETUBICS CORPORATION
发明人:
JONES, FRANK R.,BALINT, JOSEPH,LATCHMAN, YVETTE,RICE, ADRIAN,GABITZSCH, ELIZABETH
申请号:
CA3026342
公开号:
CA3026342A1
申请日:
2017.06.02
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Methods and compositions for constructing and producing recombinant adenovirus- based vector vaccines are provided. In particular aspects, there are be provided compositions and methods involving adenovirus vectors comprising genes for target antigens, such as pro state-specific antigen (PSA), pro state- specific membrane antigen (PSMA), MUCl, CEA, and/or Brachyury, and costimulatory molecules for use in treatment methods that generate highly reactive anti-tumor immune responses and that allows for multiple vaccinations in individuals with preexisting immunity to adenovirus.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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