The present disclosure is related to an Endo-Tracheal cannula holder, a novel fastening device for use the ICUs, PICUs and NICUs of several hospitals around the world for severe patients of all ages, subjected to mechanical assisted ventilation through an ETC (Endo-Tracheal cannula), also known as intubation. The present invention is different and practical, without the disadvantages of the currently known ETC fasteners. This invention does not interfere and, above all, avoids injuries, or bedsores on the patients’ skin. The present invention consists of three parts: 1. A Moustache cover or base 2. A Clip or bracket and 3. A Union piece. The Pieces I and II are joined together, by the middle line of both, through the piece number III, in three different ways: 1. with a simple hinge 2. with Velcro and 3. with a bolt. The mustache cover may be smooth or fenestrated, with anatomical shape, by its square and flat center, and slightly sloping side wings, resembling the moustache area of the patients, with rounded corners. The upper face is free and the bottom face is covered with soft thermal material as well as with sticky rubber to stick it to the patients skin. The fenestrated base allows greater ventilation and perspiration of the underlying skin. The clip can be elevated or flat. The elevated clip is canalicular, of about 2/3 of a cane. The flat clip is semicircular, of about 2/3 of a circle. Both hold one ETC at a time, of three different and consecutive sizes. The elevated clip is self-adjustable to 3 ETC sizes. The flat clip can have from one and up to three compartments. The 1-compartment clip has three ETC consecutive sizes. The ETC with three compartments has three different consecutive ETC sizes. The ETC accommodates and removed under pressure. Once the ETC is attached inside the clip, does not need to be attached with adhesive tape, but this step is optional for greater fixation security. The hinge-like ETCs allows folding the clamp and separating both piece
