A novel soybean variety, designated XB19W15R is provided. Also provided are the seeds of soybean variety XB19W15R, cells from soybean variety XB19W15R, plants of soybean XB19W15R, and plant parts of soybean variety XB19W15R. Methods provided include producing a soybean plant by crossing soybean variety XB19W15R with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB19W15R, methods for producing other soybean varieties or plant parts derived from soybean variety XB19W15R, and methods of characterizing soybean variety XB19W15R. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB19W15R are further provided.
