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MEDIZINISCHES MITTEL UND GETRÄNK/NAHRUNGSMITTEL ZUR VERHINDERUNG ZEREBRALER DYSFUNKTION
专利权人:
NIHON UNIVERSITY
发明人:
HASEGAWA, HIROYUKI,AIZAWA, SHIN
申请号:
EP11771775
公开号:
EP2562176A4
申请日:
2011.04.22
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
[Problem] To provide means for improving symptoms of cerebral dysfunction. [Solution Means] The inventor has newly found that peripheral administration of sepiapterin increases the bioavailability of aromatic monoamines in the brain. Accordingly, provided are a drug for preventing or improving cerebral dysfunction, which contains at least one of sepiapterin and its salt and food/drink for preventing or improving cerebral dysfunction, which contains at least one of sepiapterin and its salt. Unlike tetrahydrobiopterin, etc., sepiapterin is able to repress the lowering level of aromatic monoamines (such as serotonin, dopamine and noradrenaline) in neurons in the brain and also increase the bioavailability. Therefore, sepiapterin may be effective against cerebral dysfunction caused by the lowered level of aromatic monoamines in the brain in neurons in the brain, for example, central mental disorders such as depression, hyperphagia, autism, impaired consciousness and concentration, and cognitive disturbance as well as central motor disorders such as myotonia, rigidity and tremor.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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