ANTICORPS ENTIEREMENT HUMAINS DIRIGES CONTRE LE RECEPTEUR DU FACTEUR DE CROISSANCE 1 DE TYPE INSULINE

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专利权人:

IMCLONE SYSTEMS INCORPORATED

发明人:

LUDWIG, DALE L.

申请号：

CA2524305

公开号：

CA2524305C

申请日:

2004.05.03

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

This invention relates to human antibodies that bind to human insulin-likegrowth factor-1 receptor (IGF-IR), to derivatives of these antibodies (Fabs,single chain antibodies, bi-specific antibodes, or fusion proteins), and touses of the antibodies and derivatives in therapeutic, and diagnostic methods.The invention relates to nucleic acids encoding the anti-IGF-IR, methods ofgenerating the antibodies and expression. The invention further relates tocombination therapies using ant-IGF-IR antibodies with anti-neoplastic drugs.

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