TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.;CCAM BIOTHERAPEUTICS LTD.;RAMOT AT TEL-AVIV UNIVERSITY LTD.
发明人:
Gal Markel,Tehila Ben Moshe,Yair Sapir,Ilana Mandel,Jacob Schachter,Rona Ortenberg
申请号：
US14350970
公开号：
US09771431B2
申请日:
2012.10.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides antibodies, as well as molecules having at least the antigen-binding portion of an antibody, recognizing a specific epitope of the protein CEACAM1 and optionally binds also other subtypes of the CEACAM protein family. Disclosed antibodies and antibody fragments are characterized by specific CDR sequences. Methods of production and use in therapy and diagnosis, of such antibodies and antibody fragments are also provided.
