An application device for bone substitute material (K) is proposed, with a cylinder (2) in which a piston rod (3) with an elastically deformable piston (4) rests. The cylinder (2) is closed with attachment, through which a wetting liquid phase can be inserted via an injection opening. After some time, one compresses the wetted bone substitute material, with excess liquid phase being pressed out through drainage openings. Thereafter, the attachment can be removed and if applicable discharging takes place through a curved discharge nozzle (6), with the piston (4) being able to adapt itself to the curvature with the benefit of total emptying of the device.