SHIN, YOUNG KEE,HONG, SUNG YOUL,KIM, YOUNG DEUG,CHOI, JUN YOUNG,YANG, HEO BIN,PARK, HA YEON,KIM, SUNG SU
申请号:
CA3095139
公开号:
CA3095139A1
申请日:
2019.03.27
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The invention of the present application relates to a use of an antibody binding specifically to ECL-2 of claudin 3 and functional fragments thereof in cancer cell detection, diagnosis, imaging, and application to cancer treatment (anticancer use of the antibody itself, and application to ADC and CAR-expression cells (particularly immune cells)), an antibody that includes a characteristic CDR sequence exerting a remarkable effect in such uses, and a functional fragment thereof.