Luis Brito,Michelle Chan,Andrew Geall,Derek O'Hagan,Manmohan Singh,Derek OHagan
申请号:
US14130880
公开号:
US09655845B2
申请日:
2012.07.06
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention generally relates to cationic oil-in-water emulsions that can be used to deliver nucleic acid molecules, such as an RNA molecule. The emulsion particles comprise an oil core and a cationic lipid. The emulsion particles have an average diameter of about 80 nm to about 180 nm, and the emulsion have an N/P ratio of at least 1.1:1.