A new method to increase the bioavailability of health promoting compounds. More particularly the present invention relates to use of a pair of natural compounds or their synthetic versions, to obtain a composition referred hereafter in the document as NCl. The terms dissolved? or solubilize? are to be interpreted both ways as explained here in the rest of the document. NCl? helps solubilize various artificially synthesized health promoting compounds and achieve greater bioavailability, specifically in the context of topical applications and localized drug delivery for cancer tumors. If required, the artificially synthesized drug molecules can be dissolved in suitable and well known solvents that are non-toxic within the accepted levels and miscible with NCl? before combining with NCl?.