BILIC, SANELA,CAMACHO GOMEZ, JUAN ALBERTO,CAMERON, JOHN SCOTT,CASTRO-PALOMINO LARIA, JULIO CESAR,HOWARD, DANNY ROLAND JR.
申请号：
CA3051986
公开号：
CA3051986A1
申请日:
2018.02.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
This invention relates to an active metabolite of 5-bromo-2,6-di(1H-pyrazol-1-yl)pyrimindin-4-amine that modulates the activity of adenosine A2a receptor. In particular, the present invention relates to pharmaceutical compositions comprising 1-(4-amino-5-bromo-6-(1H-pyrazol-1-yl)-pyrimidin-2-yl)-1H-pyrazol-4-ol, as well as processes for its preparation and its use in the treatment of cancer alone of in combination with one or more immunotherapeutic agents.
