CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)
发明人:
REYES ORTEGA, FELISA,RODRÍGUEZ CRESPO, GEMA,AGUILAR DE ARMAS, MARÍA ROSA,GONZÁLEZ GÓMEZ, ÁLVARO,SAN ROMÁN DEL BARRIO, JULIO,SOLIS CORREA, RAÚL ENRIQUE,GARCÍA HONDUVILLA, NATALIO,BUJÁN VARELA, JULIA,CI
申请号:
EP13854481
公开号:
EP2921148A4
申请日:
2013.11.08
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The invention relates to a bioactive medical product, or dressing, characterised in that it comprises at least an inner layer formed by a hydrogel and an outer layer formed by a biodegradable and bioabsorbable polyurethane, said inner layer being impregnated with an N-terminal peptide of 20 amino acids of pro-adrenomedullin and the outer layer being impregnated with nanoparticles of bemiparin encapsulated in a biodegradable copolymer or polymer. The active components can be dosed in a sequential and controlled manner with this composition. The invention also relates to a method for producing the two-layer dressing and to the use thereof in medicine, said dressing being specially designed to treat and promote the healing of wounds, such as compromised wounds and ulcers, particularly in patients with diabetes and reduced blood supply.