SCHECKERMANN CHRISTIAN,EICHINGER DIETMAR,ARNOLD STEFAN
申请号：
IN8412/DELNP/2011
公开号：
IN2011DN08412A
申请日:
2011.10.31
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
The present invention relates to a method for purifying a recombinant follicle stimulating hormone (FSH) or recombinant FSH variant. The method comprises the steps of subjecting a liquid containing a recombinant FSH or recombinant FSH variant to an anion exchange chromatography, to a hydrophobic interaction chromatography, and to a dye affinity chromatography, wherein these chromatographies may be performed in any order, and wherein the method neither comprises a weak anion exchange chromatography nor a reverse phase chromatography. The method of purification results in a high yield of recombinant FSH having a desired degree of purity. The obtained FSH is especially useful for the prophylaxis and treatment of disorders and medical indications where FSH preparations are considered as useful remedies.
