Medical methods and systems relating to cardiovascular risk and/or performance assessment are provided. An individual performs a programmed activity of daily living such as reading displayed information aloud. The reading aloud is a temporary micro physiological challenge to the individual. The intensity of the micro challenges is gently increased over a short session. The cardiovascular (CV) response of the individual is measured during the session and is analyzed to assess a CV risk or performance of the individual. The existence of subtle CV deviations identified in the CV response of the individual may indicate a CV risk.
