ANTI-CD3 ANTIBODIES, ACTIVATABLE ANTI-CD3 ANTIBODIES, MULTISPECIFIC ANTI-CD3 ANTIBODIES, MULTISPECIFIC ACTIVATABLE ANTI-CD3 ANTIBODIES, AND METHODS OF USING THE SAME
IRVING, Bryan Allen,LA PORTE, Sherry Lynn,SAGERT, Jason Gary,HOSTETTER, Daniel Robert,RAZO, Olivia Jennifer,WHITE, Clayton,RICHARDSON, Jennifer Hope
申请号:
USUS2015/042053
公开号:
WO2016/014974A3
申请日:
2015.07.24
申请国别(地区):
WO
年份:
2016
代理人:
摘要:
The invention relates generally to antibodies, activatable antibodies, multispecific antibodies, and multispecific activatable antibodies that specifically bind to at least CD3, as well as to methods of making and using these antibodies, activatable antibodies, multispecific antibodies, and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.Linvention concerne de manière générale des anticorps, des anticorps activables, des anticorps multispécifiques et des anticorps activables multispécifiques qui se lient spécifiquement au moins à CD3, ainsi que des procédés de fabrication et dutilisation de ces anticorps, anticorps activables, anticorps multispécifiques et/ou anticorps activables multispécifiques dans diverses indications thérapeutiques, diagnostiques et prophylactiques.