isolated monoclonal antibody or antigen-binding fragment thereof, isolated antibody or antigen-binding fragment thereof, isolated dna sequence, cloning or expression vector, host cell, process for producing the antibody or antigen-binding fragment, composition , and, method of inhibiting alternative pathway complement activation in a mammal.
CHRISTI L. WOOD,GREGORY A. DEMOPULOS,HANS-WILHELM SCHWAEBLE,LARRY W. TJOELKER,MUNEHISA YABUKI,THOMAS DUDLER,W. JASON CUMMINGS
申请号：
BR112019001247
公开号：
BR112019001247A2
申请日:
2017.07.31
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
The present invention relates to masp-3 inhibitor antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of masp-3 dependent complement activation.a presente invenção refere-se a anticorpos inibidores de masp-3 e composições compreendendo tais anticorpos para utilização na inibição dos efeitos adversos da ativação do complemento dependente masp-3.
