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PRAMIPEXOLE-CONTAINING MATRIX TABLET
专利权人:
发明人:
申请号:
EP11715449.2
公开号:
EP2560622A1
申请日:
2011.04.19
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Matrix tablet comprises 0.05-5 wt.% of pramipexole or its salts, 40-80 wt.% of a matrix-forming agent comprising waxes, fats, oils, at least 13C fatty acids, fatty alcohols, monoglycerides, diglycerides and/or triglycerides, 10-50 wt.% of tableting agents, 0-25 wt.% of matrix modifiers, 0-5 wt.% of flow regulators, and 0-5 wt.% of lubricant. An independent claim is included for a method for producing the tablet matrix comprising (a) preparing a mixture comprising pramipexole or its salt, matrix forming agent, tableting agents, optionally matrix modifiers, optionally glidant and optionally lubricant, and (b) compressing the obtained product. ACTIVITY : Antiparkinsonian. MECHANISM OF ACTION : Dopamine agonist.
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