DAHL, TERRENCE C.,HUSSAIN, MUNIR A.,LIPPER, ROBERT A.,JERZEWSKI, ROBERT L.,MENNING, MARK M.,OLIYAI, REZA,YANG, TAIYIN
申请号:
TW95120444
公开号:
TWI471145B
申请日:
2006.06.08
申请国别(地区):
TW
年份:
2015
代理人:
摘要:
In accordance with this invention a novel pharmaceutical product containing efavirenz, emtricitabine and tenofovir DF are provided as a multicomponent unitary oral dosage form, component 1 comprising tenovofir DF (and, optionally, emtricitabine) and component 2 comprising efavirenz, wherein components 1 and 2 are in a stabilizing configuration. In preferred embodiments component 1 is made by dry granulation. In another embodiment a composition comprising tenovofir DF and a surfactant is claimed.