ДЕГОЙ Дэвид А. (US),ДОННЕР Памела Л. (US),КАТИ Уоррен М. (US),ХАТЧИНС Чарльз В. (US),КРЮГЕР Аллан К. (US),РАНДОЛФ Джон Т. (US),МОТТЕР Кристофер Э. (US),КРИШНАН Преетхи (US),МИСТРИ Неета К. (US),ПАЙЛОТ
申请号：
RU2011130831/04
公开号：
RU2011130831A
申请日:
2009.12.22
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A compound of formula I or a pharmaceutically acceptable salt thereof, wherein Apredstavlyaet a C-C-or carbocyclyl, 5-10 membered heterocyclyl is substituted with -X-R, wherein said CC-carbocyclyl and 5-10 membered heterocyclic are optionally substituted by one or more R Apredstavlyaet a C-C-or carbocyclyl, 5-10 membered heterocyclyl is substituted with -XR, wherein said CC-carbocyclyl and 5-10 membered heterocyclic are optionally substituted with one or more R each of hee Xyavlyaetsya independently selected from a bond, -L-, -O-, -S- or -N (R) - each R of R is independently selected from hydrogen, -L, CC-carbocyclyl and 5-10 membered heterocyclyl, wherein in each case the presence of each of said CC-carbocyclyl and 5-10 membered heterocyclyl is optionally substituted with one or more R each Zyavlyaetsya of Z and independently selected from a bond, -C (RR) -, -O-, -S- or -N (R) - each of W, W, Wi Wyavlyaetsya independently selected from N or C (R), where R b each occurrence is independently selected from hydrogen or R each of R Ryavlyaetsya independently selected from hydrogen or R each of R Ryavlyaetsya Nez dently selected from hydrogen or R or R together with the carbon atoms to which they are attached form a CC-carbocyclic or 5-10 membered heterocyclic ring, wherein said carbocyclic and CC-5-10 membered heterocyclic rings are optionally substituted by one or more R each of r and Ryavlyaetsya independently selected from hydrogen or R or R together with the carbon atoms to which they are attached form a CC-carbocyclic or 5-10 membered heterocyclic ring, wherein said carbocyclic and CC-5-10 membered geterotsik
